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In addition, iron ions initiate the growth of synovial pannus by regulating the expression of critical genes such as c-myc and mdm2

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Count:60

Taken together with the studies in knockout and transgenic GPx1 models, these findings suggest a role for GPx1 in the regulation of insulin and glucose metabolism and suggest that modulation of selenoprotein expression, including GPx1, may influence metabolism in humans, as well